Elective nodal radiotherapy in prostate cancer

In patients with prostate cancer who have a high risk of pelvic nodal disease, the use elective whole pelvis radiotherapy is still controversial. Two large, randomised, controlled trials (RTOG 9413 and GETUG-01) did not show benefit over prostate-only radiotherapy. 2020, POP-RT trial established role in more than 35% lymph node invasion (known as Roach formula). stressed importance patient selection. cN1 (clinically positive) disease or pN1 (pathologically addition to androgen deprivation therapy significantly improved survival compared alone, shown retrospective studies. This population might increase future because sensitive prostate-specific membrane antigen PET–CT will become standard staging procedure. Additionally, SPORTT suggested biochemical recurrence-free salvage setting. A correct definition upper field border, which should include bifurcation abdominal aorta, key As result using modern technology, severe late urinary intestinal toxic effects are rare do seem cutoff for cancer?In their recent Review paper The Lancet Oncology, Gert De Meerleer colleagues take comprehensive look at evidence irradiation cancer.1 Specifically, clinically node-negative cancer, value (WPRT) has been discussed length. For least 20%, showed significant improvement control, disease-free survival, metastasis-free WPRT. Full-Text PDF